In this example there is a module named rc-pinnacle-pctv-hd that should be blacklisted.

Connect with SSH to your LibreELEC box.

list all used modules (search for rc, ir or cir)

lsmod

add blacklisted module to blacklist.conf

echo "blacklist rc-pinnacle-pctv-hd" > /storage/.config/modprobe.d/blacklist.conf

and reboot